FOSCAVIR® Foscarnet 24 mg/ml (250 ml) injection
|Name||FOSCAVIR® Foscarnet 24 mg/ml (250 ml) injection|
|Description||Foscarnet is an antiviral agent with a broad spectrum inhibiting all known human viruses of the herpes group: herpes simplex virus type 1 and 2; human herpes virus 6; varicella zoster virus; Epstein-Barr virus and cytomegalovirus (CMV) and some retroviruses, including human immunodeficiency virus (HIV) at concentrations not affecting normal cell growth. Foscarnet also inhibits the viral DNA polymerase from hepatitis B virus.|
|Active Ingredient||Foscarnet trisodium hexahydrate|
|Indication||Foscavir is indicated for induction and maintenance therapy of cytomegalovirus (CMV) retinitis in patients with AIDS.
Foscavir is also indicated for the treatment of mucocutaneous Herpes Simplex Virus (HSV) infections, clinically unresponsive to aciclovir in immunocompromised patients. The safety and efficacy of Foscavir for the treatment of other HSV infections (e.g. retinitis, encephalitis); congenital or neonatal disease; or HSV in immunocompetent individuals has not been established.
The diagnosis of aciclovir unresponsiveness can be made either clinically by treatment with intravenous aciclovir (5-10 mg/kg t.i.d) for 10 days without response or by in vitro testing.
Foscavir is not recommended for treatment of CMV infections other than retinitis or HSV or for use in non-AIDS or non-immunocompromised patients.
|Strengths||Foscarnet trisodium hexahydrate 24 mg/ml|